Chemists have achieved what a new article calls a 'landmark in drug discovery' with the total synthesis of 11.5g of halichondrin. Known to be a potent anti-cancer agent in mouse studies, and found naturally in sea sponges -- though only ever in minuscule quantities -- the halichondrin class of molecule is so fiendishly complex that it had never been synthesized on a meaningful scale in the lab.
from Latest Science News -- ScienceDaily http://bit.ly/31CHcvP
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Monday, June 17, 2019
Harvard chemists' breakthrough in synthesis advances a potent anti-cancer agent
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