By activating just eight genes for transcription factors, researchers have directly converted mouse stem cells into oocyte-like cells that mature and can even be fertilized like egg cells. In addition to giving new insight into egg cell development, the research may lead to a simple route for generating large amounts of oocyte cytoplasm for use in reproductive biology and medicine.
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Wednesday, December 16, 2020
Oh so simple: Eight genes enough to convert mouse stem cells into oocyte-like cells
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