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Thursday, September 23, 2021

An estrogen receptor that promotes cancer also causes drug resistance

Cancer cells proliferate despite a myriad of stresses -- from oxygen deprivation to chemotherapy -- that would kill any ordinary cell. Now, researchers have gained insight into how they may be doing this through the downstream activity of a powerful estrogen receptor. The discovery offers clues to overcoming resistance to therapies like tamoxifen that are used in many types of breast cancer.

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