Researchers have identified a novel protein complex that regulates Aurora B localization to ensure that chromosomes are correctly separated during cell division. The complex, NWC, is made up of three proteins: NOL11, WDR43, and Cirhin. In the absence of NWC, Aurora B did not accumulate at centromeres, and chromosome movement and alignment were impaired. Together, these results show that NWC is required for faithful chromosome segregation.
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Saturday, June 27, 2020
New protein complex gets chromosomes sorted
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